APOQUEL 16MG CHW #1 Prescribed Oral Medicine for Allergic Itch [1]: Apoquel Chewable is a revolutionary oral medicine for dogs with allergic itch. Apoquel can be used short-term or for long-term maintenance therapy [2,3] in dogs 12 months of age and older. Apoquel Chewable is expected to provide comparable efficacy to Apoquel Tablet after the first dose, and comparable safety to Apoquel Tablet [4,5]. Stops allergic itch at the source [6]: Apoquel is not a steroid, antihistamine, or cyclosporine (a type of drug that reduces immune system activity). Apoquel is in a different category of medications. Unlike other medicines, Apoquel blocks allergic itch at the source. So, it works at the underlying cause of itch to provide relief fast. Fast-Acting Allergy Itch Relief: If your dog is scratching, licking, or chewing like crazy, you want to provide fast, effective relief. Apoquel Chewable controls it within 24 hours [2]. Can be used with many other medications [5] including: nonsteroidal anti-inflammatory drugs (NSAIDs), vaccines (such as rabies), and allergen-specific immunotherapy (allergy shots or drops). Available in Three Strengths: Apoquel Chewable comes in 3.6 mg, 5.4 mg, and 16 mg based on your dog’s body weight. Follow your veterinarian’s instructions for dosing as prescribed. You can administer to your dog orally once a day. Apoquel Chewable is a tasty pork-liver flavor. Apoquel is also available in a tablet formulation. IMPORTANT SAFETY INFORMATION: Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or those with serious infections. Apoquel and Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel and Apoquel Chewable have not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel and Apoquel Chewable have been used safely with many common medications including parasiticides, antibiotics and vaccines. See full Prescribing Information for Apoquel Tablet at ApoquelPI.com and full Prescribing Information for Apoquel Chewable at ApoquelChewablePI.com. INDICATIONS: Control of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. *Vets, n=250, Pet Owners, n=491 References: 1. Data on file, PetTrak Total Unique Patient Count, December 2022, Zoetis Inc. (TI-09437); 2. Data on file: Study Report A161C-US-21-C02, Zoetis Inc., 2022 (TI-09898); 3. Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35. doi:10.1111/vde.12194 (AR-01949) 4. Data on file: Study Report A461N-US-21-B66, Zoetis Inc. 2022; 5. FOI Apoquel Chewable FOI Summary: 2023/06/09 Original NADA 141-555 (v2.0); 6. Gonzales AJ, Bowman JW, Fici GJ, et al. Oclacitinib (APOQUEL)is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. J Vet Pharmacol Therapy. 2014;37(4)317-24. doi:10.1111/jvp.12101 (AR-00542); 7. Data on file, Apoquel Cytopoint Vet Tracker Wave 11 (December 20 2018) (TI-04447); 8. Data on file, APOQUEL/CYTOPOINT Pet Owner Tracker Wave 11, 2022, Zoetis Inc. (TI-08418)


